Welcome to the Breslow lab in the Department of Molecular, Cellular & Developmental Biology at Yale University

  • We use functional genomic tools to dissect biological processes at the cellular and molecular level.
  • Our main focus is the mammalian primary cilium, a cellular structure that serves as a signal transduction center in development and disease.
  • Combining new screening technologies with biochemical reconstitution and cell-based microscopy assays, we are pursuing a range of questions at the interface of organelle biology, signal transduction and cell cycle control.


June 28, 2017
Our genome-wide CRISPR-based screen for Hedgehog pathway regulators is now on bioRxiv. Lots of new insights into cilia, centrioles, ciliopathies and more!
June 19, 2017
Margaret Kennedy joins the lab as a post-graduate associate!  Margaret just earned her B.S. at The College of New Jersey, where she studied splicing in yeast in the lab of...
January 1, 2017
On Jan. 1, 2017, the Breslow lab officially kicked off.  Dr. David Breslow is a newly appointed Assistant Professor in Yale’s Department of Molecular, Cellular &...